Chemistry - Chemistry (CHEM) 105 - The unique chemistry of cats’ guts make them the perfect host for Toxoplasma gondii

This data would possibly enable Toxoplasma researchers to change from workplace research laboratory science lab science laboratory, workplace, work cats to lab rats


Toxoplasma Gondi could be a common parasite that causes Associate in Nursing infection referred to as infection in roughly third of humans, therefore analysis during this space is vital to human health. T. Gondi’s lifecycle is curiously advanced, and it's gained infamy for its tendency to breed within the intestines of cats. The explanation for this exceptional specificity has antecedently been unknown. Now, a study printed in PLOS Biology in August has known the precise molecular parts within the feline bowel that make the conditions necessary for the parasite to breed.

The analysis found that a chemical referred to as linoleic acid is important for the sexual lifecycle of T. Gondi. Associate in nursing catalyst within the intestines of most mammals referred to as delta-6-desaturase sometimes helps convert linoleic acid to arachidonic acid. However cats are the sole craniate familiar to lack this catalyst in their guts – thus, their guts maintain high enough levels of linoleic acid to permit for the parasite to succeed in sexual maturation. Once the researchers patterned this out, they found the way to prevent the activity of delta-6-desaturase in mice, which suggests that within the future they'll be ready to stop victimization cats – a degree of competition with animal rights activists – within the laboratory. Eventually they'll even be ready to grow T. Gondi in cell culture to be told additional concerning this common (and, some say, mind-controlling) parasite.

 

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StudyUp Author: daniellee Lee
Major: Maths, Physics, Chemistry

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